Study finds years of exposure to air pollution, road traffic noise may increase risk of heart failure



The results of a new study suggest that exposure to air pollution and road traffic noise over many years may be associated with an increased risk of developing heart failure.

The correlation appears to be even greater in people who are former smokers or have high blood pressure. These research results were published in the Journal of the American Heart Association, an open access journal of the American Heart Association.

“We have found that long-term exposure to specific air pollutants and road traffic noise increases the risk of incident heart failure, especially for former smokers or people with hypertension, preventive measures and Education is therefore needed, ”said Youn-Hee Lim, PhD, lead author of the study and assistant professor in the environmental health section of the public health department at the University of Copenhagen in Copenhagen, Denmark. “To minimize the impact of these exposures, broad public tactics such as emission control measures should be implemented. Strategies such as smoking cessation and blood pressure control should be encouraged to help reduce individual risk. “

This analysis examined the impact of long-term environmental exposure, in particular to air pollution and road traffic noise, on the development of heart failure in a group of nurses in Denmark on a period of 15 to 20 years.

The researchers collected data from a prospective study of more than 22,000 members of the Danish All-Female Nursing Cohort Study. The women were aged 44 and over at the time of enrollment in the study and lived in Denmark.

The participants were recruited in 1993 or 1999, and upon registration, each woman completed a comprehensive questionnaire on body mass index, lifestyle factors (smoking, alcohol consumption, physical activity and habits. food), pre-existing health problems, reproductive health and working conditions. .

Information on heart failure diagnoses was gathered throughout the 20-year follow-up by linking study participants to the Danish National Patient Register, which includes records of all healthcare provided in Danish hospitals. . Patient data was collected until December 31, 2014.

The study group lived in rural, urban and suburban areas across Denmark. To best measure individual exposure to air pollution and road traffic noise, the researchers kept records of each individual’s residential addresses, including any moves to new residences between 1970 and 2014.

To determine the levels of air pollution, the annual average concentrations of two components, fine particles (PM2.5) and nitrogen dioxide (NO2) were measured using a Danish pollution modeling system atmospheric. Road traffic noise levels within a three-kilometer radius of participants’ residential addresses were estimated using a validated model system called Nord2000 and measured in decibels (dB), the standard unit for the sound intensity.

Analysis of various pollutants and their effects on incident heart failure revealed:

For every 5.1 µg / m3 increase in fine particulate matter exposure over three years, the risk of incident heart failure increased by 17%. For every 8.6 µg / m3 increase in NO2 exposure over three years, the risk of incident heart failure increased by 10%. For every 9.3 dB increase in exposure to road traffic noise over three years, the risk of incident heart failure increased by 12%; and increased exposure to fine particles and former smoker status were associated with a 72 percent increased risk of incident heart failure.

“We were surprised at how two environmental factors – air pollution and road traffic noise – interacted,” Lim said. “Air pollution was a bigger factor in the incidence of heart failure compared to traffic noise; however, women exposed to both high levels of air pollution and traffic noise showed the greatest increased risk of heart failure. In addition, approximately 12% of the total study participants suffered from hypertension at the time of enrollment in the study. However, 30 percent of nurses with heart failure had a history of hypertension, and they were the population most susceptible to exposure to air pollution. “

The study has several limitations. The researchers did not have information on other variables that might have affected the results of the analysis, such as measures of individual exposure to indoor air pollution or occupational noise; time spent outdoors; glass thickness of their home windows, which can influence noise pollution levels; if they had a hearing impairment; or individual socio-economic status.

In addition, almost a quarter of the initial participants in the Danish nursing cohort were excluded from the final analysis because information was missing at the start or end of the study, so selection bias may be. a contributing factor.

The researchers also note that, since they studied the exposure levels and health effects of Danish nurses, a generalization of the results to men or other populations warrants caution.

Previous research has shown an association between air pollution and cardiovascular disease, and the American Heart Association detailed a collection of research on pollution risks in a science statement in 2004, with additional updated results. added in 2010.

In 2020, the American Heart Association American Heart Association released a scientific statement and policy guidance to address the implications of air pollution amid the COVID-19 pandemic and beyond. The policy statement discusses policy directions at the local, state and federal levels to improve the health of our communities. Short-term exposure to high levels of certain air pollutants has also been linked to heart failure.

The co-authors are Jeanette Therming Jorgensen, M.Sc., Ph.D .; Rina So, Ph.D. student; Tom Cole-Hunter, Ph.D .; Amar Mehta, Sc.D .; Heresh Amini, Ph.D .; Elvira Brauner, Ph.D .; Rudi Westendorp, MD, Ph.D.; Shuo Liu, MPH; Laust Mortensen, Ph.D .; Barbara Hoffmann; Steffen Loft, DMSc .; Matthias Ketzel, Ph.D.; Ole Hertel, D.Sc .; Jorgen Brandt, Ph.D .; Steen Solvang Jensen, Ph.D .; Claus Backalarz; Mette K. Simonsen, M.Sc .; Nebojsa Tasic; Matija Maric; and Zorana J. Andersen, Ph.D. Authors’ disclosures are in the manuscript.

The study was funded by the Danish Council for Independent Research, the Region Zealand Fund and the Novo Nordisk Foundation Challenge Program.

(With entries from ANI)

Disclaimer: This article was posted automatically from an agency feed without any text changes and has not been reviewed by an editor

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