PCORI Board of Directors approves $ 49.5 million to fund ne

WASHINGTON, DC – The Board of Governors of the Patient-Centered Outcomes Research Institute (PCORI) today approved two lists of research grants totaling $ 49.5 million to support nine new comparative clinical efficacy research studies ( CER) aimed at improving care for adults and children in a range of health conditions. Three of these CER studies totaling $ 23.5 million focus on telehealth and mHealth strategies, the future of which is currently the subject of much clinical and policy discussions.

“With the explosion of telehealth, particularly during the COVID-19 pandemic, studies evaluating how telehealth strategies work in different settings are highly relevant to many Americans, and we eagerly await the information gleaned from these studies. as well as all other news. approved research projects, ”said PCORI Executive Director Nakela L. Cook, MD, MPH. study on improving care for people living with intellectual and developmental disabilities.

The recently approved ERC telehealth studies will expand an existing strong portfolio of PCORI-funded research determining the effectiveness of telehealth for a wide range of conditions and situations.

A new CER study will assess the effectiveness of two new mHealth technologies in helping people quit smoking. He will compare the use of an mHealth approach for cognitive behavioral therapy (CBT) called iCanQuit alone to a combination of iCanQuit and Motiv8, a technology that offers financial rewards based on evidence of smoking abstinence, and each from these telehealth options to traditional withdrawal approaches. such as telephone counseling through “stop lines”.

CER study on pain adaptation seeks to determine whether a single online course called Empowered Relief that teaches pain relief techniques is as or more effective than the benchmark treatment of eight sessions of CBT in helping people how to manage their chronic pain and whether either therapy is working better. for some people than for others. If the online class proves to be as effective, it could increase access to care by offering a less restrictive means of developing coping skills.

As evidence accumulates that yoga can help people with mild to moderate depression feel better, this study will compare results among people who participate in a real-time distance yoga program to those who receive a yoga program. recommended form of psychotherapy called behavioral activation by video conference or telephone. .

Additional CER studies approved for funding include:

  • The CARES trial, which will compare the use of a low-dose opioid regimen to the use of a nonsteroidal anti-inflammatory drug (NSAID) regimen to see what works best to help patients relieve their pain as they recover at home after surgery that is low risk and has the least damage.
  • A CER study that will use real-world data from nearly 400,000 medical records to determine whether detecting and treating genital herpes infection in early pregnancy reduces the risk of genital herpes infection. birth among African Americans and racial disparities in maternal outcomes. Current guidelines recommend treating genital herpes infection later in pregnancy with the goal of protecting newborns from the risk of viral transmission.
  • A CER study that will help parents of youth with intellectual and developmental disabilities choose which of two peer group interventions – one focused on support and information sharing and the other with the same goal but adding a advocacy skills training – best improves health outcomes for themselves and their children.

Details of these and all other studies approved for funding can be found on the PCORI website. All funding awards have been approved pending review of activities and programs by PCORI staff and the issuance of formal award contracts. With these latest awards, PCORI has invested approximately $ 3.3 billion to fund patient-centered BLR and to support other projects designed to improve CBR methods and the infrastructure needed to rigorously conduct BLR. and efficient.

Targeted funding, three-year funding commitment plan and research program

In addition to approving the award lists, the Board also approved the development and publication by the PCORI of two targeted funding announcements for the PCORI in 2022. One will provide up to $ 30 million to fund projects. studies comparing the effectiveness of ways to prevent or treat alcohol use in 12-year-olds. to 17. The other will provide up to $ 30 million for research evaluating interventions to prevent, early detect or treat delirium in the elderly.

They will be part of an ambitious three-year funding commitment plan totaling $ 1.8 billion that the Council approved today. This plan includes $ 1.5 billion for research studies, $ 180 million for dissemination and implementation projects, and $ 160 million for projects related to infrastructure and research acceleration. on patient-centered outcomes.

Similarly, the PCORI is preparing to open a public comment period on its proposed research agenda with Board approval to solicit comments on this proposed framework for making progress on its national priorities. health issues and guide the ongoing development of a research project program with patients and stakeholders. grab.

About the PCORI

The Patient-Centered Outcomes Research Institute (PCORI) is an independent, not-for-profit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers, and clinicians with the evidence-based information needed for care. better informed health care providers. the decisions. The PCORI is committed to continuously seeking input from a wide range of stakeholders to guide its work.


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